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Carafate is an anti-ulcer medication that works by forming a complex that covers the ulcer site, which protects it from acid, so that it can heal. Generic and brand drugs with 100% satisfaction guaranteed. 1 g sucralfate forms a coating over ulcers, protecting the area from further injury. (soo-KRAL-fate) COMMON BRAND NAME (S): Carafate. The medication has been shown to raise blood sugar levels, so it is important to know how quickly it works Over - the-counter antacids, such as Gelusil, Maalox, Mylanta, Rolaids and Tums, may provide quick relief. It is fda approved only for duodenal ulcers. This protects the ulcer from the acid of the stomach, allowing it to heal. Called H-2-receptor blockers, these medications include cimetidine. Sucralfate forms a coating over ulcers, protecting the area from further injury. 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